sensorimotor Nenropathy In Children With Collagen Diseases
Trez Boshra Kamel;
Abstract
Sensorimotor neuropathies have been reported in patients with known or suspected connective tissue disease.
By means of electroneurophysiological studies (SSEP, NCV), it is easy to evaluate the integrity of peripheral nerves, the spine and the central pathways.
Early SSEPs recording in patients with rheumatoid arthritis can detect early compression of medulla oblongata or spinal cord with or without atlantoaxial sublaxation. Furthermore, SSEPs study in lupus patients even asymptomatic ones, can detect nervous system involvement.
This study aimed at evaluation of nervous system affection in SLE and JRA patients, and its correlation with clinical manifestations and laboratory investigations.
Patients included in this study were attending regularly the Allergy and Immunology Clinic, Children's Hospital, Ain Shams University. They were 27 females (80 %) and 7 males (20%), their ages ranged from 7 to 24 years. They were divided into two groups; group I: included 19 SLE patients and group II included
15 JRA patients.
Group III included I 0 apparently healthy age and sex matched subjects for comparison.
All patients included in this study were subjected to:
Thorough history taking and clinical examination, laboratory investigations including complete blood count (CBC), ESR measurement, complete urine analysis for albuminuria, hematuria and casts, kidney function tests including: serum creatinine and blood urea nitrogen (BUN), serum ANA, anti DNA antibodies (for SLE patients only) and rheumatoid factors (for JRA patients).
By means of electroneurophysiological studies (SSEP, NCV), it is easy to evaluate the integrity of peripheral nerves, the spine and the central pathways.
Early SSEPs recording in patients with rheumatoid arthritis can detect early compression of medulla oblongata or spinal cord with or without atlantoaxial sublaxation. Furthermore, SSEPs study in lupus patients even asymptomatic ones, can detect nervous system involvement.
This study aimed at evaluation of nervous system affection in SLE and JRA patients, and its correlation with clinical manifestations and laboratory investigations.
Patients included in this study were attending regularly the Allergy and Immunology Clinic, Children's Hospital, Ain Shams University. They were 27 females (80 %) and 7 males (20%), their ages ranged from 7 to 24 years. They were divided into two groups; group I: included 19 SLE patients and group II included
15 JRA patients.
Group III included I 0 apparently healthy age and sex matched subjects for comparison.
All patients included in this study were subjected to:
Thorough history taking and clinical examination, laboratory investigations including complete blood count (CBC), ESR measurement, complete urine analysis for albuminuria, hematuria and casts, kidney function tests including: serum creatinine and blood urea nitrogen (BUN), serum ANA, anti DNA antibodies (for SLE patients only) and rheumatoid factors (for JRA patients).
Other data
| Title | sensorimotor Nenropathy In Children With Collagen Diseases | Other Titles | التهابات الأعصاب الحسية الحركية فى الأطفال الذين يعانون من أمراض النسيج الضام | Authors | Trez Boshra Kamel | Issue Date | 2001 |
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