VALUE OF SERUM AND CERVICO-VAGINAL GLYCODELIN LEVELS AS AN IMPLANTATION MARKER IN ICSI CYCLES

Abstract

• Out of the 50 patients included in the study; 25 patients had positive serum ß-hCG 2 weeks after ET but only 18 patients of them had intrauterine gestational sac(s) with positive fetal pulsations by u/s scan 2 weeks later. • the level of serum glycodelin was significantly higher in the group of women who had positive biochemical pregnancy test than in those with negative biochemical pregnancy test (P value: 0.014) and the same was found as regard cervico-vaginal glycodelin level (P value: 0.008). • Serum glycodelin had a statistically significant higher levels in patients who had positive clinical pregnancy than in those who didn’t (P value: 0.001) and there was also a statistically significant difference between the two groups as regard cervico-vaginal glycodelin levels (P value: 0.007). • There’s a statistically significant week correlation between serum and cervico-vaginal glycodelin levels (P value: 0.012). • There’s a moderate statistically significant correlation between serum glycodelin level and both implantation rate (P value: <0.001) and number of gestational sacs (P value: <0.001) and a weaker statistically significant correlation between cervico-vaginal glycodelin level and both implantation rate (P value: 0.006) and number of gestational sacs (P value: 0.007). • There’s no statistically significant difference between serum and cervico-vaginal glycodelin levels in correlation to implantation rate (P value: 0.511) or number of gestation sacs (P value: 0.437).