Recent Updates in Sleep Disorders Related to Neurological Diseases
Nermin Kamal El-SayedHiggy;
Abstract
The number of centers and neurotransmitters, which contribute in the sleep and wake process, is very vast, thus explaining the very common comorbidity between different neurological diseases & sleep disorders.
Sleep disorders are common and affect sleep quality and quantity, leading to increased morbidity. They adversely affect mood and quality of life in general population. Thus, they are expected to have particularly disruptive effects in patients with neurological impairment. Sleep disorders may precede some neurological diseases, years before they clinically appear.
In controlled studies, volunteers who were restricted to four to five hours of sleep for a few days experienced worsening neurocognitive, behavioral, metabolic, and autonomic parameters. Several studies demonstrate that sleep deprivation leads to alterations in immune function with increased risk of infection, including pneumonia. Additionally, chronic sleep deprivation is associated with increased risk of diabetesmellitus, cardiovascular disease, cancer, and mortality. Adults average, relatively, low hours of sleep each night, less than the seven to nine hours recommended by many sleep experts. Sleep disorders can lead to increased morbidity and higher health carecosts.
In Epilepsy, sleep deprivation has seizure-provoking effects, while frequent seizures may in turn lead to sleep fragmentation. The presence of seizures, even when they occur during wakefulness, can disturb sleep, as can epilepsy per se.
Anti-epileptic drugs (AEDs) c
Sleep disorders are common and affect sleep quality and quantity, leading to increased morbidity. They adversely affect mood and quality of life in general population. Thus, they are expected to have particularly disruptive effects in patients with neurological impairment. Sleep disorders may precede some neurological diseases, years before they clinically appear.
In controlled studies, volunteers who were restricted to four to five hours of sleep for a few days experienced worsening neurocognitive, behavioral, metabolic, and autonomic parameters. Several studies demonstrate that sleep deprivation leads to alterations in immune function with increased risk of infection, including pneumonia. Additionally, chronic sleep deprivation is associated with increased risk of diabetesmellitus, cardiovascular disease, cancer, and mortality. Adults average, relatively, low hours of sleep each night, less than the seven to nine hours recommended by many sleep experts. Sleep disorders can lead to increased morbidity and higher health carecosts.
In Epilepsy, sleep deprivation has seizure-provoking effects, while frequent seizures may in turn lead to sleep fragmentation. The presence of seizures, even when they occur during wakefulness, can disturb sleep, as can epilepsy per se.
Anti-epileptic drugs (AEDs) c
Other data
| Title | Recent Updates in Sleep Disorders Related to Neurological Diseases | Other Titles | المستجدات الحديثة في اضطرابات النوم المتعلقة باللأمراض العصبية | Authors | Nermin Kamal El-SayedHiggy | Issue Date | 2014 |
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