Comparison between the Effect of Carbetocin, Oxytocin and Misoprostol on Decreasing Blood Loss during and After Cesarean Section

Abstract

Postpartum hemorrhage (PPH) is a potentially life-threatening complication of both vaginal and cesarean delivery, The prevalence of PPH is approximately 6% of all deliveries (Carroli et al., 2008). The most frequent cause of PPH is uterine atony, therefore, active management of the third stage of labor rather than expectant management is recommended (Chong et al., 2004). Postpartum hemorrhage, defined as blood loss of 500 ml or more and severe PPH as 1000 ml or more in the third stage of labor, is an important cause of maternal mortality (accounting for nearly one quarter of all maternal deaths worldwide), While there is general agreement on the beneficial effects of active management of the third stage of labor, several issues which are yet to be resolved, such as clear definitions on the individual components of the intervention, the best methods and the requirements for the safe administration of this intervention under conditions of limited resources. Generally, injectable oxytocin has been