Telomerase Activity in Normal Leukocytes and Hematological Malignancies
Hanan Abd El-Majeed Mohamed;
Abstract
The end of chromosome in higher eukaryote are termed telomere. Telomeric DNA consists of tandemly repeated DNA sequences which are gradually lost with age and with replication in vitro (Martens et al., 2000).
Telomerase is a specialized, ,reverse transcriptase that catalyzes elongation of the telomeric tandem repeat, TTAGGG, by addition of this sequence to the ends of existing telomeres (Masutoni et al., 2000).
Telomerase is a specialized, ,reverse transcriptase that catalyzes elongation of the telomeric tandem repeat, TTAGGG, by addition of this sequence to the ends of existing telomeres (Masutoni et al., 2000).
Other data
| Title | Telomerase Activity in Normal Leukocytes and Hematological Malignancies | Other Titles | نشاط انزيم التيلوميريز فى خلايا الدم الطبيعية وسرطانات الدم | Authors | Hanan Abd El-Majeed Mohamed | Issue Date | 2001 |
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