Role of diffusion and perfusion MR imaging In the diagnosis of acute ischemic brain diseases

Abstract

This study highlights the applicability and technique of examination of both diffusion weighted imaging and perfusion weighted imaging. Perfusiou-weighted imaging (PWI) lesion estimates the region of acute dysfunctional brain tissue_ whereas the acute diffusion-weighted imaging (OWl) lesion appears to correspond to the core of the early infarction. The mismatch between the acute PWI lesion and the smalier D"'+:VI lesion represents potentially salvageable brain tissue (an estimate of the ischemic penumbra). ln patients with a P\VI/D\VI mismatch_ early repertusion is often associated with substantial clinical improvement and reversal or reduction ofD\\'l l sion growth_