"(N-ACETYL B-D-GLUCOSAMINIDASE IN AMNIOTIC FLUID AND URINE OF PATIENTS OF PREECLAMPSIA WITH OR WITHOUT INTRA UTRINE GROWTH RETARDATION (IUCR"

Ragab EI-Bendary EI-Mettwally Ryaa


Abstract


N-acetyi-B-D-glucosaminidase in both unne and amniotic fluid (NA,G) is one of the suggested potentially useful enzymes . It is a hydrolytic enzyme. It is widely distributed in most mammalian tissues and fluids . High concentration are found in the lysosomal fraction of the proximal renal tubular cells, with a small amount in the microsomal fraction .• Estimation of both amniotic fluid NAG urinary NAG is improtant in diagnosis and preeclampsia, In this study, NAG urine have been estimated two times, one in the third trimester and the other 24-48 hours after labour for 30 patients and in their ammiotic fluids in the last 3 months of pregnancy . Twenty p preeclamptic patients, ten mild preeclampsia and ten severe preeclampsia compared with ten normal pregnancy females . A. highly significant increase in both Amniotic fluid NAG the mean of urinary NAG and NAG/urine creatinine ratio in all preeclamptic patients . (46,91 gm/L-6.20gm/mmol respectively) compared to control group (22.17 gm/L-2.03/mmol respectively) . But a significant decrease in the mean of urine creatinine in all preeclamptic patients (9.15 mmol/L) compai•ed to control group ( 11.01 mmol/L) .


Other data

Other Titles "دراسة ن – أسيتيل – بيتاد – جلوكوز أمينديز فى السائل الامنيوسى لمرضى سابق التشنج الحملى المصحوب أو غير المصحوب بتخلف النمو الجينينى داخل الرحم "
Issue Date 2000
URI http://research.asu.edu.eg/handle/12345678/37586


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