Epidemiology of Hypertension in Haemodialysis Egyptian Patients and Prevalent Antihypertensive Drugs Used

Abstract

Summary T he purpose of our study was to describe the epidemiology of hypertension in haemodialysis Egyptian patients and Prevalent antihypertensive drugs used. Hypertension was defined as an average predialysis SBP >140 mmHg or DBP >90 mmHg, or the use of anti-hypertensive medications. Pre-dialysis and post-dialysis BP goals should be < 140/90 mmHg and < 130/80 mmHg, respectively. Our study comprised 150 ESRD patients and all were on regular HD as a replacement therapy for CRF, 78 of whom were men (♂) and 72 were women (♀). In our study The prevelance of HTN was 44%. The mean change between both pre- and post-dialysis systolic and diastolic BP is significant. This significant reduction of post-dialysis BP, indicates that the prevalence of HTN was significantly associated with volume excess as proved by comparing clinical data of our patients. Correction of ECV overload with UF has led to the DW concept, which is the post-dialysis body weight that allows BP to remain normal until the next dialysis session, without the need for anti-hypertensive medication and despite IDWG. BP is the key indicator of ECV and is used to set the body weight target at each dialysis session. Normalization of BP indicates normalization of ECV, usually with a lag-time. An effective HTN therapeutic strategy in HD patients must include:  Increase time of HD,  Strict control of DW and  Prevention and treatment of others CV risk factors. Management of hypertension with drugs in dialysis patients:  Drugs that inhibit the renin-angiotensin system, such