Serum Apelin Levels in Obese Children and Adolescents and its Relation to Cardiac Function and Lipid Profile
Shereen Marie Zaied Abd Elgaber;
Abstract
The aim of this work was to estimate serum levels of apelin among
obese children and adolescents and to determine the relationship between these levels and blood
pressure, lipid profile and the cardiac function in
these children.
This study was a cross-sectional study that was carried out in Ain
Shams University-Children Hospital and National Research Center
(NRC), during the period between December 2011 to April 2013.
The study included 50 overweight and obese children and adolescents who diagnosed according
to BMI.
Forty age and sex matched normal healthy non obese children
participated in this study and served as controls.
Both groups were subjected to the following:
Detailed history
Anthropometric assessment
Right arm sitting systolic and diastolic blood pressure
Blood samples for determination of: Random blood sugar, Serum high ,density lipoprotein,
Serum cholesterol, Serum triglyceride (TG), Low density lipoprotein ( LDL-C), Plasma Apelin-12
level using (ELISA) and High sensitive C – Reactive protein (Hs-crp) .
Echocardiography using (GE vivid 3 and vivid 7) to assess the following:
- Left ventricular function: thickness of interventricular septum in diastole (IVSd), thickness
of left ventricular
posterior wall in diastole (LVPWd), left v
obese children and adolescents and to determine the relationship between these levels and blood
pressure, lipid profile and the cardiac function in
these children.
This study was a cross-sectional study that was carried out in Ain
Shams University-Children Hospital and National Research Center
(NRC), during the period between December 2011 to April 2013.
The study included 50 overweight and obese children and adolescents who diagnosed according
to BMI.
Forty age and sex matched normal healthy non obese children
participated in this study and served as controls.
Both groups were subjected to the following:
Detailed history
Anthropometric assessment
Right arm sitting systolic and diastolic blood pressure
Blood samples for determination of: Random blood sugar, Serum high ,density lipoprotein,
Serum cholesterol, Serum triglyceride (TG), Low density lipoprotein ( LDL-C), Plasma Apelin-12
level using (ELISA) and High sensitive C – Reactive protein (Hs-crp) .
Echocardiography using (GE vivid 3 and vivid 7) to assess the following:
- Left ventricular function: thickness of interventricular septum in diastole (IVSd), thickness
of left ventricular
posterior wall in diastole (LVPWd), left v
Other data
| Title | Serum Apelin Levels in Obese Children and Adolescents and its Relation to Cardiac Function and Lipid Profile | Other Titles | مستوى الابيلين فى الاطفال و المراهقين المصابين بالسمنة و علاقته بوظائف القلب و مستوى الدهون فى الدم | Authors | Shereen Marie Zaied Abd Elgaber | Issue Date | 2014 |
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