Physiological Studies of Psidium guajava Leaf Extract and Glibenclamide Drug on Streptozotocin Induced Diabetic Male Albino Rats
Omnia Nasr Abdelrhman Mohamed;
Abstract
Abstract
The present study was conducted to evaluate the anti-diabetic effect of aqueous extract of guava leaf using streptozotocin–induced diabetic rat. It also compares between the antidiabetic efficacy of guava leaf extract, glibenclamide and their combinations. The present aim was achieved by measuring the serum levels of glucose and insulin together with the histopathological and immunohistochemical changes in pancreatic tissue and insulin content in β cells. The present study extended to investigate the changes in the functions of liver, kidney and lipid profile in the rat model of diabetes, rat model of diabetes treated with guava leaf extract, glibenclamide and their combinations.
The present study was conducted to evaluate the anti-diabetic effect of aqueous extract of guava leaf using streptozotocin–induced diabetic rat. It also compares between the antidiabetic efficacy of guava leaf extract, glibenclamide and their combinations. The present aim was achieved by measuring the serum levels of glucose and insulin together with the histopathological and immunohistochemical changes in pancreatic tissue and insulin content in β cells. The present study extended to investigate the changes in the functions of liver, kidney and lipid profile in the rat model of diabetes, rat model of diabetes treated with guava leaf extract, glibenclamide and their combinations.
Other data
| Title | Physiological Studies of Psidium guajava Leaf Extract and Glibenclamide Drug on Streptozotocin Induced Diabetic Male Albino Rats | Authors | Omnia Nasr Abdelrhman Mohamed | Issue Date | 2018 |
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