EFFECT OF SOME FREE RADICALS ON BIOMOLECULES, AND PROTECTIVE ROLE OF SOME ANTIOXIDANT

Abstract

The present study was concerned mainly with the antioxidant activity of some phenolic compounds, aniline compounds and heterocyclic compounds by two different methods. The relationship between the chemical structure and the antioxidant activity was studied. Finally, studying the protective role of the most active tested groups using linoleic acid model was investigated. The obtained results are classified into two parts. The obtained results from part one could be summarized in the following: 1- The investigated phenolic compounds included 36 compounds, which the chemical structures are varied. Aniline compounds group included 17 different compounds. The structural differences among aniline compounds involved type of substituent on the aromatic ring which is varied in the number and the position on the ring. Heterocyclic compounds group included 11 different compounds. This group included vitamin C (L-ascorbic acid) and vitamin E (α-tocopherol). The structural differences among heterocyclic compounds included type of heterocyclic ring, beside number and position of the substituents on the ring.