TNF-alpha promoter -308 and PTPN22 C1858T genes polymorphisms in Systemic lupus erythematosus

Asmaa Mohamed kamal Ibrahem;

Abstract


Summary, Conclusion & Recommendations


SLE is a complex polygenic disease characterized by loss of tolerance to self antigens, particularly nuclear antigens, leading to activation of autoreactive B and T cells, formation of autoantibodies and deposition


Other data

Title TNF-alpha promoter -308 and PTPN22 C1858T genes polymorphisms in Systemic lupus erythematosus
Other Titles الاشكال المتعددة فى جينى تى إن إف الفا -308 و بى تى بى إن 22 سى 1858 تى فى حالات الذئبة الحمراء
Authors Asmaa Mohamed kamal Ibrahem
Keywords TNF-alpha promoter -308 and PTPN22 C1858T genes polymorphisms in Systemic lupus erythematosus
Issue Date 2012
Description 
Summary, Conclusion & Recommendations


SLE is a complex polygenic disease characterized by loss of tolerance to self antigens, particularly nuclear antigens, leading to activation of autoreactive B and T cells, formation of autoantibodies and deposition

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