Assessment of Vitamin D Levels in Women with Polycystic Ovarian Syndrome

Abstract

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age, with a prevalence of 6–10% in the general population. PCOS is characterized by the following: ovulatory dysfunction resulting in oligo-amenorrhea and/or anovulation, hyperandrogenism and/or hirsutism, and the presence of polycystic ovarian morphology by ultrasound . Vitamin D also plays a physiologic role in reproduction including ovarian follicular development and luteinization via altering anti-müllerian hormone (AMH) signalling, follicle-stimulating hormone sensitivity and progesterone production in human granulosa cells. Studies comparing vitamin D levels between patients with PCOS and healthy women with normal ovulation have yielded conflicting results. Hence, the present study aimed to know if there will be a relationship between PCOS and vitamin d deficiency. Objective: is to compare the levels of vitamin D in women with PCOS and healthy fertile women.