A Study on the Potential Chemomodulatory Effects of Biochanin- A in Hepatocellular Carcinoma Cells
Mohi el-din Magdy Mahmoud Youssef;
Abstract
Biochanin-A, a promising isoflavone, is a natural chemopreventive with selective toxicity towards cancer cells only. Sorafenib is considered as the first-line therapy for patients with advanced hepatocellular carcinoma (HCC). The current study was designed to investigate the synergistic cytotoxicity of biochanin-A (Bio-A) combined with sorafenib (SOR) in HepG2 human hepatocellular carcinoma cell line through modulating pro-survival and apoptotic pathways. Bio-A alone showed cytotoxic potentiality against HepG2 cells at relatively lower potency (IC
Other data
| Title | A Study on the Potential Chemomodulatory Effects of Biochanin- A in Hepatocellular Carcinoma Cells | Other Titles | دراسة التاثير الكيماوى المعدل لبيوكانين - أ فى خلايا سرطان الكبد | Authors | Mohi el-din Magdy Mahmoud Youssef | Issue Date | 2013 |
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