Metabolic Syndrome and Psychiatric Profile in a Sample of Egyptian Patients with Obstructive Sleep Apnea
Sarah Ashraf Mohamed;
Abstract
Summary
O
bstructive sleep apnea is one of the most serious prevalent conditions that have significant morbidity and mortality when untreated, current prevalence of OSA pointed that one third of the sleep studies showed some degree of OSA.
Regarding medical complications, studies indicate that obstructive sleep apnea might be a risk factor for both metabolic syndrome and psychiatric illness.
Regarding the metabolic profile, Patients with obstructive sleep apnea appear to suffer from the disorders which characterize the metabolic syndrome, as they have hypertension, high fasting blood glucose levels, increased waist circumference, low HDL cholesterol and high triglycerides and many other characteristics, including sympathetic activation, endothelial dysfunction, systemic inflammation, and hyper coagulation and insulin resistance.
And so the metabolic syndrome might be the final common pathway connecting sleep apnea with cardiovascular diseases.
As for psychiatric profile, many researchers studied the association of sleep apnea (OSA) with psychiatric pathology with higher prevalence of depression, anxiety and nocturnal panic attacks. Psychiatric co-morbidity in OSA may affect patient quality of life and adherence to CPAP.
Based on that, this study was conducted aiming to study the effect of OSA on metabolic and psychiatric profile.
Sample selection:
1. Selection of cases:
Thirty patients (males and females) were selected from the outpatient sleep clinic in the Institute of Psychiatry, Ain Shams University and approving to participate in this study as the case group.
Their age ranges between 18-55 years. Diagnosed by polysomnogram as having obstructive sleep apnea Patients with Axis I psychiatric disorders according to DSM IV, co morbid major physical illness or history of neurological diseases were excluded from the study.
Control group:
A control group of 30 individuals of volunteers were formed for the case control comparison. They were matched with the patient group for age and sex and with no apparent physical or psychiatric morbidity.
2. Method:
Procedures and tools:
The study took place from the 1st of august 2013 till 31st of December 2015.
All the outpatients in the sleep clinic were examined to determine eligibility for participation in the study.
Screening was conducted through clinical psychiatric interview according to outpatient psychiatric sheet of Ain Shams University Institute of Psychiatry, which examined demographic data, psychiatric history, sleep history and examination as well as medical history information.
All patients will be offered written informed consent before conducting any procedure.
O
bstructive sleep apnea is one of the most serious prevalent conditions that have significant morbidity and mortality when untreated, current prevalence of OSA pointed that one third of the sleep studies showed some degree of OSA.
Regarding medical complications, studies indicate that obstructive sleep apnea might be a risk factor for both metabolic syndrome and psychiatric illness.
Regarding the metabolic profile, Patients with obstructive sleep apnea appear to suffer from the disorders which characterize the metabolic syndrome, as they have hypertension, high fasting blood glucose levels, increased waist circumference, low HDL cholesterol and high triglycerides and many other characteristics, including sympathetic activation, endothelial dysfunction, systemic inflammation, and hyper coagulation and insulin resistance.
And so the metabolic syndrome might be the final common pathway connecting sleep apnea with cardiovascular diseases.
As for psychiatric profile, many researchers studied the association of sleep apnea (OSA) with psychiatric pathology with higher prevalence of depression, anxiety and nocturnal panic attacks. Psychiatric co-morbidity in OSA may affect patient quality of life and adherence to CPAP.
Based on that, this study was conducted aiming to study the effect of OSA on metabolic and psychiatric profile.
Sample selection:
1. Selection of cases:
Thirty patients (males and females) were selected from the outpatient sleep clinic in the Institute of Psychiatry, Ain Shams University and approving to participate in this study as the case group.
Their age ranges between 18-55 years. Diagnosed by polysomnogram as having obstructive sleep apnea Patients with Axis I psychiatric disorders according to DSM IV, co morbid major physical illness or history of neurological diseases were excluded from the study.
Control group:
A control group of 30 individuals of volunteers were formed for the case control comparison. They were matched with the patient group for age and sex and with no apparent physical or psychiatric morbidity.
2. Method:
Procedures and tools:
The study took place from the 1st of august 2013 till 31st of December 2015.
All the outpatients in the sleep clinic were examined to determine eligibility for participation in the study.
Screening was conducted through clinical psychiatric interview according to outpatient psychiatric sheet of Ain Shams University Institute of Psychiatry, which examined demographic data, psychiatric history, sleep history and examination as well as medical history information.
All patients will be offered written informed consent before conducting any procedure.
Other data
| Title | Metabolic Syndrome and Psychiatric Profile in a Sample of Egyptian Patients with Obstructive Sleep Apnea | Other Titles | المتلازمة الأيضية والجوانب النفسية لعينة مصرية من مرضى انقطاع النفس الانسدادي النومي | Authors | Sarah Ashraf Mohamed | Issue Date | 2015 |
Recommend this item
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.