Synovial Tissue Tumors
Ashraf M. El-Sayed;
Abstract
Synovial tissue is a thin delicate modified connective tissue that lines the non-articular regiOns of the Synovial joints, bursae and tendon sheaths.
Synovium is formed from a development of cavities in a pre existing mesenchyme. It varies considerably in appearance, depending on tilt local mecl1anical factors and the nature oft he underlying tissue. For instance, the synovial smface of joints subjected to high pressure is flat, while synovium under less stress has a redundant surface.
A variety of benign and malignant tumours anse from the synovnnn. Benigu tumours encountered included synovial lipoma, hemangioma and fibroma
Synovial sarcoma is the primary malit,mant synovial tissue tumour of the highest clinical significance, it constitutes 5-l 5% of all sarcomas. It principally affects young adults, with almost three fourths of the patients being younger than 40 years.
Extra-Synovial sites of origin, combined with electron microscopic and immunohistochemical studies of synovial sarcomas that show differences hom normal synovial tissue, have convinced some that, the tenn synovial sarcoma is a misnomer that should be eliminated in favor of "carcinosarcoma" of soft tissue.
Despite the evidence indicating the lack of origin ti•om synovial tissue, there is no advantage in changing the name of this lesion, especially since synovial sarcoma is a term that is so well ingrained in the
literature.
Other miscellaneous primary malignant tumors include epithelioid
sarcoma, chondrosarcoma nnd clear cell sarcoma.
Synovium is formed from a development of cavities in a pre existing mesenchyme. It varies considerably in appearance, depending on tilt local mecl1anical factors and the nature oft he underlying tissue. For instance, the synovial smface of joints subjected to high pressure is flat, while synovium under less stress has a redundant surface.
A variety of benign and malignant tumours anse from the synovnnn. Benigu tumours encountered included synovial lipoma, hemangioma and fibroma
Synovial sarcoma is the primary malit,mant synovial tissue tumour of the highest clinical significance, it constitutes 5-l 5% of all sarcomas. It principally affects young adults, with almost three fourths of the patients being younger than 40 years.
Extra-Synovial sites of origin, combined with electron microscopic and immunohistochemical studies of synovial sarcomas that show differences hom normal synovial tissue, have convinced some that, the tenn synovial sarcoma is a misnomer that should be eliminated in favor of "carcinosarcoma" of soft tissue.
Despite the evidence indicating the lack of origin ti•om synovial tissue, there is no advantage in changing the name of this lesion, especially since synovial sarcoma is a term that is so well ingrained in the
literature.
Other miscellaneous primary malignant tumors include epithelioid
sarcoma, chondrosarcoma nnd clear cell sarcoma.
Other data
| Title | Synovial Tissue Tumors | Other Titles | اورام النسيج السينوفى | Authors | Ashraf M. El-Sayed | Issue Date | 2000 |
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