Guillian Barre Syndrome

Mohammed Sabry Mohammed;

Abstract


One of the earliest descriptions of what we know today as

Guillain-Barre syndrome was found in Landry's report on

10 patients with "ascending paralysis" in 1859.


In 1916 Guillain, Barre, and Strohl described two French soldiers with motor weakness, areflexia, and "albuminocytological dissociation" in the cerebrospinal fluid, (Seneviratne, 2000). Subsequently several · cases with similar manifestations were reported, and this clinical entity was named after Guillain and Barre.

In 1986, Feasby and co-workers reported that, some patients who were considered to have GBS, had axon loss rather than segmental demyelination (SO) as their underlying pathophysiology; these cases have been labeled the acute axonal form of GBS. More recently, it has been appreciated that this subdivision must be further separated into two groups: the first with both motor and sensory fibers affected, labeled the acute motor-sensory axonal neuropathy pattern (AMSAN), and the second \\ th only motor fibers affected, particularly at the root level, labeled the acute motor axonal neuropathy pattern or acute motor neuropathy (AMAN) (Griffin et al., 1995).


Other data

Title Guillian Barre Syndrome
Other Titles متلازمة جيلان بارية
Authors Mohammed Sabry Mohammed
Issue Date 2006

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