Causing Resistance to Oxacillin and Ofloxacin Among Clinical Lsolates of MRSA
Amal SAalah Safoh;
Abstract
In this study 470 S. au reus were isolated from 2400 different
clinical samples with ft•equency of 20 'X..
S 30 oxacillin resistantS. aureus, were isolated from 470 S. aureus
samples with frequency of 6 %. 8
Isolation of an oxacillin resistant strain was associated with :- 8
S 1- Longer duration of hospitalization before the culture date .,
2- Any indwelling catheter on the day the referent culture was
performed. P value <0.0001 (highly significant). 8
S$ _",_ A ny antt.- mt.crobt.a I t I1erapy. 8
S P value <0.005 (highly significant) . f.
5-Residence in the medical or coronary intensive care units i
S P value <0.05 (significant). 8
sS In this study aminoglycosides intake, llouroquinolones, oral 28
S vancomycin, penicillin, antacids and insulin requiring diabetes are 2
S m.
st.gnt.I.1. can t
. (P va Iue > 0.05). ?8
ORSAB Was comparable to disk diffusion method . It could serve as i
S an accurate, easy to perform , and time saving alternative to the disk '?_
S diffusion test . However it is expensive . 2
is Recommendations :- i8
si l-13ccausc or the increase in antimicrobial resistance among a number of 2
S important pathogens, better surveillance systems are needed in hospitals 8
and in the community to identify risk factors for spread of resistance and
Ss hei1cc to dc!ine preventive strategies to control resistant organisms. 2
S 2-Strict use of highly active antibiotics is necessary to extend their useful• t8
i life.
1t 3-Continued development of new bio-active agent that are effective, g
sS specific, stable, are needed. 8
iS Development of new biotechnologies for antibacterial drugs, may provide
clinical samples with ft•equency of 20 'X..
S 30 oxacillin resistantS. aureus, were isolated from 470 S. aureus
samples with frequency of 6 %. 8
Isolation of an oxacillin resistant strain was associated with :- 8
S 1- Longer duration of hospitalization before the culture date .,
2- Any indwelling catheter on the day the referent culture was
performed. P value <0.0001 (highly significant). 8
S$ _",_ A ny antt.- mt.crobt.a I t I1erapy. 8
S P value <0.005 (highly significant) . f.
5-Residence in the medical or coronary intensive care units i
S P value <0.05 (significant). 8
sS In this study aminoglycosides intake, llouroquinolones, oral 28
S vancomycin, penicillin, antacids and insulin requiring diabetes are 2
S m.
st.gnt.I.1. can t
. (P va Iue > 0.05). ?8
ORSAB Was comparable to disk diffusion method . It could serve as i
S an accurate, easy to perform , and time saving alternative to the disk '?_
S diffusion test . However it is expensive . 2
is Recommendations :- i8
si l-13ccausc or the increase in antimicrobial resistance among a number of 2
S important pathogens, better surveillance systems are needed in hospitals 8
and in the community to identify risk factors for spread of resistance and
Ss hei1cc to dc!ine preventive strategies to control resistant organisms. 2
S 2-Strict use of highly active antibiotics is necessary to extend their useful• t8
i life.
1t 3-Continued development of new bio-active agent that are effective, g
sS specific, stable, are needed. 8
iS Development of new biotechnologies for antibacterial drugs, may provide
Other data
| Title | Causing Resistance to Oxacillin and Ofloxacin Among Clinical Lsolates of MRSA | Other Titles | دراسة تحليلية لعوامل الخطورة المسببة فىحدوث مقاومة الاوكساسيلين والافلوكساسين فى البكتريا العنقودية المقاومة للميثيسيلين | Authors | Amal SAalah Safoh | Issue Date | 2001 |
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