Endoscopic and Pathological Study for Portal Hypertensive Gastro-Duodenopathy before and After Esophageal Variceal Eradication Using Endoscopic Band Ligation

Abstract

Portal hypertension (PHT) is a frequent manifestation of liver cirrhosis, and it can cause various pathological changes in the entire gastrointestinal (GI) tract (from the esophagus to the anus). The complications that most directly result from portal hypertension are the development of varices and variceal hemorrhage. Apart from gastro-esophageal varices PHT may lead to portal hypertensive gastropathy (PHG), enteropathy and colopathy. Endoscopic therapeutic interventions like sclerotherapy and band ligation have changed the outlook for patients with variceal bleeding; however band ligation has shown better results in terms of variceal obliteration and fewer side effects In view of excellent results of band ligation as far as obliteration and eradication of esophageal varices is concerned, its effect on development or worsening of portal hypertensive gastropathy and duodenopathy has raised concern among endoscopists. In this regard, the present study aimed to evaluate the endoscopic and pathological changes of portal hypertensive gastropathy and duodenopathy after obliteration of esophageal varices by band ligation.  Summary 104 The study was conducted at the Tropical Medicine Department, Tropical outpatient clinic and Endoscopy Unit at Ain-Shams University Hospitals. Fifty patients were selected and enrolled according to the inclusion and exclusion criteria. All subjects includ