EVALUATION OF SOME SCHISTOSOMICIDAL DRUGS ANDFISH OIL AGAINST THE DEVELOPMENT OF SCHISTOSOMIASIS MANSONI IN ALBINO MICE
Nahla El-Sayed El-Shazly;
Abstract
It has been known that bilharziasis mansoni is a very
.serio't1s disease and unfortionately it is endemic in Egypt This disease is dangerous because it might lead to liver fibrosis during several years after the first infection if not diagnosed and treated early.
The liver fibrosis results from the inflammation caused by the eggs deposited by the worms in the liver sinusoids. These eggs secrete an antigen that elicits production of lymphokines by T- lymphocytes by which recruitment of inflammatory •cells occur. The complete h>Tanuloma 1s composed of CD4+, CD8+T cells and few of mast cells, neutrophils, oesinophils, and giant cells, epitheloid cells macrophages, B-cells and fibroblasts. Thus the• granulomatous reaction is of delayed hypersensitivity type.
.serio't1s disease and unfortionately it is endemic in Egypt This disease is dangerous because it might lead to liver fibrosis during several years after the first infection if not diagnosed and treated early.
The liver fibrosis results from the inflammation caused by the eggs deposited by the worms in the liver sinusoids. These eggs secrete an antigen that elicits production of lymphokines by T- lymphocytes by which recruitment of inflammatory •cells occur. The complete h>Tanuloma 1s composed of CD4+, CD8+T cells and few of mast cells, neutrophils, oesinophils, and giant cells, epitheloid cells macrophages, B-cells and fibroblasts. Thus the• granulomatous reaction is of delayed hypersensitivity type.
Other data
| Title | EVALUATION OF SOME SCHISTOSOMICIDAL DRUGS ANDFISH OIL AGAINST THE DEVELOPMENT OF SCHISTOSOMIASIS MANSONI IN ALBINO MICE | Other Titles | تقييم كفاءة بعض العقاقير المميتة للبهارسيه وفاعلية زيت السمك ضد مرض البلهارسيا المعوية فى الفئران البيضاء | Authors | Nahla El-Sayed El-Shazly | Issue Date | 2000 |
Recommend this item
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.