RANDAN study of invasive bacterial --• -•- •- infections in• children aged from 1- 60 months in Suez governorate

Abstract

This hospital-based surveillance study ofiBI in children below 5 years age admitted to study centers between the beginning of February 1999 and the end of February 2000. 632 children with the selection criteria were included. Male represents 55.6%. Patients aged 2 years old or less represent about 60%, majority of cases of meningitis and septi­ • cemia were in this age group, while pneumonia was distributed among different age groups Most patients were living in urban areas.

Pneumonia, meningitis and septicemia represent 83.2%, 13% and

3.8% respectively.

Preterm delivery, low birth weight, early weaning and malnutrition were marked associated with cases of meningitis and septicemia, but to lesser extent with pneumonia, the difference was statistical significant, while presence of smokers in the family and large family size and crowd­ ing were more associated with pneumonia than meningitis and septicemia, the difference was statistical significant. About 71% of patients had his­ tory of antibiotic intake in the last 48 hours before admission; this percent was statistical significant lower than that found among patients who were blood cultures positive that was 28%. That indicates marked effect of an­ tibiotic intake on microbiological yield of blood cultures. Majority of cases of pneumonia (86.7%) was presented with severe and very severe condition. All cases of meningitis were presented with fever, lethargy and poor

feeding, while 85% were presented with convulsion and neck rigidity.

Over 60% of cases of septicemia had history of previous admission in the last 10 days, 93.3% of them had had history of different diagnosis.