Relation Between Helicobacter Pylori And Iron Deficiency Anemia In Hemodialysis Patients

Abstract

Anemia develops early in the course of CKD and is nearly universal in patients with ESRD; anemia contributes to poor quality of life in patients with CKD. Fortunately, among the disorders that may affect patients with ESRD, anemia is the most responsive to treatment. Anemia in ESRD patients on hemodialysis mainly due to deficiency of erythropoietin synthesis or iron deficiency, anemia should be evaluated in order to identify any reversible process, the most common reversible cause is iron deficiency. In the general population observational studies have shown a link between H. pylori and iron deficiency, often resulting in iron deficiency anemia. Thisstudy was conducted to assess the frequency of H.pylori infection in hemodialysis population and to identify the possible relation between H. pylori infection andiron deficiency anemia in hemodialysis population Thisstudy included 90 HD patients randomly selected from dialysis unit in Kafr El-Sheikh General hospital; it was found that H. pylori stool antigen is positive in 50 patients (55.6%), while was negative in 40 patients (44.4%). No significant difference was found between infected and non-infected patients for hematocrit or hemoglobin levels, neither for iron, TIBC, ferritin nor T.sat. In the present study, we have assessed dyspeptic symptoms without observing statistically significant differences between both groups. In this study, no significant differences observed between the groupsabout albumin levels or inflammatory parameters analyzed (C- reactive protein).