EFFECT OF SOME ENVIRONMENTAL STRESSORS ON GROWTH,DEVELOPMENT AND BEHAVIOUR OF EXPERIMENTAL ANIMALS

Abstract

Insecticides cause a marked environmental pollution particularly in the farm vegetables ; residues may be toxic to livestock , in addition they cause many toxic effects to many farm workers and to general public. Manifestations of this toxicity are represented by delayed neurotoxicity, mutagenicity, teratogenesis and carcinogenesis (Durham and Williams,l972; Gupte eta! .,1985 and Courtiney et al.,1986). Insecticides may be carried in many tissues of human and animals ,which cause many troubles affecting growth ,development and pregnancy (Uphous eta!.,1985 and Simmon ,1986). The exhaust gas induces stressing action similar to the classical activation of the pituitary adrenal axis with increase of relative adrenal weight and the rate of corticosteroid production . After chronic exposure, deep metabolic changes appear which reflect accentuated state of exhaustion . Moreover, interruption of spermatogenesis with azoospermia is noted. Vianna et al.(l984) reported that exposure of fathers to autoexhaust may be of etiologic importance for leukaemia in children . Thus, exhaust gas could be considered as a very potent toxic agent ( El Feki et a1.,1984). The present investigation was conducted to study the effect of insecticides and autoexhaust on rats. In order to record their effects the fo11owing physiological monitors were used : *Clinical symptoms and mortalities.

*Growth