The Impact of Comorbidities on the Outcome of Tuberculous Patient in Respiratory Intensive Care Unit
Marwa Hassan AL Makawy;
Abstract
Pulmonary TB requiring ICU care is rare accounting to 1-3% of all TB cases, but commonly known to be of markedly bad prognosis. Up to our knowledge this was the first Egyptian study to deal with active pulmonary tuberculosis inside ICU.
This study aimed to describe and determine the mortality rate and co morbidities associated with mortality in patients with active pulmonary tuberculosis requiring Respiratory ICU admission.
This is a retrospective-prospective study design started in November 2016 in which adult patients (> 16 years) with active pulmonary TB previously or subsequently admitted to the Respiratory ICU (RICU) of Abbassia Chest Hospital between November 2014 to October 2016 (retrospective part) and between November 2016 to April 2017 (prospective part) respectively were included.
Patients who stay or stayed at RICU less than 24 hours or presenting with inactive pulmonary TB or extrapulmonary TB were excluded. TB treatment in the hospital is according to WHO and national guidelines. Demographic, clinical, radiological and therapeutics characteristics were obtained from the medical records.
A total of 43 patients were included, of 43 patients studied, 35 (81%) died during ICU stay.
The results of current study revealed that the mean age of the non survived group 45.5 ± 17.2. Male patient were more common than females 34 (79,1%), and females were 9 (20,9%). There was no significant difference between survivors and non-survivors regarding sex. X-Ray finding non significantly affects the mortality rate in current study, bilateral lung infiltration in 46.51% of the patient and unilateral lung infiltration 53.39% and mortality was 54.29%, 45.71 % respectively. 11of 43 patient (25,58% of the cases) had LCF and they all died 100% which affect the mortality rate significantly 31,4%. DM, renal failure, HIV and malignancy were accompanied with high, but non significant mortality rate 14.29%, 20%, 17.14%, 8.57% respectively. Mechanical ventilation in current study affected rate of death significantly (80%). The significant cause of death in current study was the ventilatory causes in 28 patients (80% of total mortality). Non survivors had significant high APACHEII SCORE 21.4±6.2 than servivors.
e
This study aimed to describe and determine the mortality rate and co morbidities associated with mortality in patients with active pulmonary tuberculosis requiring Respiratory ICU admission.
This is a retrospective-prospective study design started in November 2016 in which adult patients (> 16 years) with active pulmonary TB previously or subsequently admitted to the Respiratory ICU (RICU) of Abbassia Chest Hospital between November 2014 to October 2016 (retrospective part) and between November 2016 to April 2017 (prospective part) respectively were included.
Patients who stay or stayed at RICU less than 24 hours or presenting with inactive pulmonary TB or extrapulmonary TB were excluded. TB treatment in the hospital is according to WHO and national guidelines. Demographic, clinical, radiological and therapeutics characteristics were obtained from the medical records.
A total of 43 patients were included, of 43 patients studied, 35 (81%) died during ICU stay.
The results of current study revealed that the mean age of the non survived group 45.5 ± 17.2. Male patient were more common than females 34 (79,1%), and females were 9 (20,9%). There was no significant difference between survivors and non-survivors regarding sex. X-Ray finding non significantly affects the mortality rate in current study, bilateral lung infiltration in 46.51% of the patient and unilateral lung infiltration 53.39% and mortality was 54.29%, 45.71 % respectively. 11of 43 patient (25,58% of the cases) had LCF and they all died 100% which affect the mortality rate significantly 31,4%. DM, renal failure, HIV and malignancy were accompanied with high, but non significant mortality rate 14.29%, 20%, 17.14%, 8.57% respectively. Mechanical ventilation in current study affected rate of death significantly (80%). The significant cause of death in current study was the ventilatory causes in 28 patients (80% of total mortality). Non survivors had significant high APACHEII SCORE 21.4±6.2 than servivors.
e
Other data
| Title | The Impact of Comorbidities on the Outcome of Tuberculous Patient in Respiratory Intensive Care Unit | Other Titles | تأثير الأمراض المصاحبة على مرضي الدرن الرئوي في وحدة الرعاية المركزة للأمراض الصدرية | Authors | Marwa Hassan AL Makawy | Issue Date | 2017 |
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