Correlation of Serum Magnesium with Dyslipidemia in Non Diabetic Chronic kidney disease Patients

Abstract

In patients with CKD, dyslipidemia is a very common complication; disturbances in lipid metabolism are seen even at the early stages of CKD and subsequently progress with the deterioration of renal function. Serum magnesium level may be elevated, normal or decreased in CKD patients. These alterations of magnesium balance increase with the advanced stages of CKD. Data have shown a correlation between serum magnesium concentration and dyslipidemia in CKD patients by altering lipid metabolism and these alterations might contribute to the dramatic increase in cardiovascular events and mortality observed in the CKD population. So, this study was conducted to assess the association between serum Mg level and lipid parameters in CKD patients with stage 4, stage 5 predialysis and stage 5 on hemodialysis. This study included 60 CKD patients randomly selected from outpatient clinic and dialysis unit in El- Mansoura New General Hospital and classified as group 1: 20 patients with stage 4, group 2: 20 with stage 5 predialysis and group 3: 20 with stage 5 on hemodialysis.