Anti-Helicobacter Pylori Antibodies in Serum of Women with Unexplained Infertility
Mohamed Osama Abd Al Gani;
Abstract
Unexplained infertilityrepresents a significant clinical problem, the evaluation and management of which leave a lot to be desired. The lack of universally accepted diagnostic criteria makes it difficult to study this problem because of the heterogeneity in the samples selected for study. Agreement on the definitions is a first step in this process of creating homogeneous groups for study.
The Practice Committee of the American Society for Reproductive Medicine (ASRM) has published guidelines for a standard infertility evaluation. It includes semen analysis, assessment of ovulation, hysterosalpingiogram, andlaparoscopy. When the results of a standard infertility evaluation are normal, practitioners assign a diagnosis of unexplained infertility. Although estimates vary, the likelihood that all test results for an infertile couple are normal (i.e. the couple has unexplained infertility) is approximately 15% to 30%.
Couples should then undergo comprehensive evaluation, before decisions regarding treatment can be made. Agreement on this process among investigators will improve the understanding of this disorder and will pave the way for more valid and useful studies on treatment efficacy.
Infertility affects about 13% to 15% of couples worldwide and unexplained infertility represents one of the most common diagnoses in the field of fertility care. Unexplained infertility accounts is approximately 15% to 30%.
The definition, valuable diagnostic approach and appropriate management among women withunexplained infertility remain controversial. Appropriate diagnostic testing of novel causes for unexplained infertility may decrease the percentage of patients suffering unexplained infertility.
H. pylori is a Gram-negative bacterium responsible for the large majority of chronic gastritis, peptic ulcers and mucosal-associated lymphoid tissue (MALT) lymphoma. The pathogenicity of H. pylori infection depend on the inflammatory response to chronic infection, which is thought to be determined by many factors, including the strain-specific factors, the host's immune response, and environmental factors.
The Practice Committee of the American Society for Reproductive Medicine (ASRM) has published guidelines for a standard infertility evaluation. It includes semen analysis, assessment of ovulation, hysterosalpingiogram, andlaparoscopy. When the results of a standard infertility evaluation are normal, practitioners assign a diagnosis of unexplained infertility. Although estimates vary, the likelihood that all test results for an infertile couple are normal (i.e. the couple has unexplained infertility) is approximately 15% to 30%.
Couples should then undergo comprehensive evaluation, before decisions regarding treatment can be made. Agreement on this process among investigators will improve the understanding of this disorder and will pave the way for more valid and useful studies on treatment efficacy.
Infertility affects about 13% to 15% of couples worldwide and unexplained infertility represents one of the most common diagnoses in the field of fertility care. Unexplained infertility accounts is approximately 15% to 30%.
The definition, valuable diagnostic approach and appropriate management among women withunexplained infertility remain controversial. Appropriate diagnostic testing of novel causes for unexplained infertility may decrease the percentage of patients suffering unexplained infertility.
H. pylori is a Gram-negative bacterium responsible for the large majority of chronic gastritis, peptic ulcers and mucosal-associated lymphoid tissue (MALT) lymphoma. The pathogenicity of H. pylori infection depend on the inflammatory response to chronic infection, which is thought to be determined by many factors, including the strain-specific factors, the host's immune response, and environmental factors.
Other data
| Title | Anti-Helicobacter Pylori Antibodies in Serum of Women with Unexplained Infertility | Other Titles | الأجسام المضادة لبكتريا هيليكوباكتر بيلوري في دم السيدات ذوات العقم غير معروف السبب | Authors | Mohamed Osama Abd Al Gani | Issue Date | 2014 |
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