Electrochemical Studies on Some Pharmaceutical compounds

Amany Tawfik Hassan;

Abstract


Isoniazid, Ranitidine, Ketoprofen, Captopril, Terfenadine, Praziquentel and Loratadine are pharmaceutical compounds of great biological importance. In this thesis, it is aimed to study the electrochemical behaviour of these compounds in buffer solutions of different pH values to elucidate their electrode reaction mechanisms. It is aimed also to optimize the experimental and instrumental conditions for the trace quantitative determination of these compounds in their dosage forms and in human serum using cathodic adsorptive stripping voltammetry technique.


The thesis comprises of three main chapters:



Chapter I : It presents a general introduction of the electrochemical analysis of pharmaceutical compounds and short notes on the principles of the different electrochemical techniques used in the present study. Also, it presents a literature survey on the pervious electrochemical and analytical studies of the investigated pharmaceutical compounds.


Chapter II: It contains the experimental part. It describes the materials, preparation of the various solutions used in the present study. This chapter contains also description of the instrumentations used in the present measurements such as de-polarography, cyclic voltammetry, coulometry, differential pulse polarography and cathodic adsorptive stripping voltammetry.


Other data

Title Electrochemical Studies on Some Pharmaceutical compounds
Other Titles دراسات كهروكيميائية على بعض المركبات الصيدلانية
Authors Amany Tawfik Hassan
Issue Date 1999

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