Effects of Low-Level Laser on Gamma-Irradiated Rats

Abstract

Adverse health effects associated with radiation exposure have been known for decades, and ionizing radiation exposure has been linked with a broad range of different types of cancer and benign neoplasms as well as birth defects, reproductive effects, and diseases of the circulatory, hematologic, and neurologic systems (Assadi et al., 2014; Sannino et al., 2014; Shore, 2014; Won & Lee, 2014). Everyone is exposed to natural and manmade ionizing radiation that can originate from sources in the environment and in medical and occupational settings (Simon & Linet, 2014). The development of safe and more effective radioprotectors is crucial in view of their potential application during unintended radiation exposure and radiotherapy (Baker et al., 2011). Still, currently, there is no safe and effective non-toxic radioprotector available for humans (Xu et al., 2014). The main aim of the present study was to determine the possible therapeutic effects of low-level laser as He-Ne laser against radiation induced oxidative stress, hematological, biochemical and histological alterations in male Wister albino rats.