The Effect of Topical Application of Lidocaine – Prilocaine Cream on Pain Relief During Episiotom
Afifi Ali Ali Al-Afifi;
Abstract
Choice of method of analgesia, suture material, suture technique and the operator's surgical competence can influence short and long term morbidity related to perineal repair (Johanson and Kettle, 2000).
Perineal infiltration with local anesthetics is the most common technique to provide anesthesia during perineal suturing. Although infiltrative anesthesia remains a main stay for pain relief goals during minor surgical procedures, topical anesthetics in the form of sprays, goles, and ointment have emerged as a valuable alternative in several medical specialties (Kaweskis, 2008).
The advantages of using topical anesthetics include their localized action with negligible systemic absorption, case of administration, painless application, and absence of edema at the surgical site that distorts wound margins in laceration repair.
Lidocaine-prilocaine cream (EMLA cream; AstraZeneca, Basiglio, Italy) is an eutectic mixture of 2.5% lidocaine and 2.5% prilocaine that is used widely as topical anesthetic for pediatric, dermatologic, reconstructive, and gynecologic minor procedures. Absorption from the genital mucosa is rapid, and onset time is between 5 and 10 minutes with an average duration of effective analgesia from 15-20 minutes; however, on intact skin, the cream should be applied for at least 1 hour to provide satisfactory dermal analgesia
Safety and efficacy of EMLA cream have been shown consistently in a number of clinical trials across many medical specialities since 1990 (Kaweski, 2008; Friedman et al., 2001).
EMLA cream provides analgesia by the release of lidocaine and prilocaine, which are two amide anesthetics, from the cream into the dem1al layers before penetrating the smooth and striated muscle and the individual axons within the nerve.
Perineal infiltration with local anesthetics is the most common technique to provide anesthesia during perineal suturing. Although infiltrative anesthesia remains a main stay for pain relief goals during minor surgical procedures, topical anesthetics in the form of sprays, goles, and ointment have emerged as a valuable alternative in several medical specialties (Kaweskis, 2008).
The advantages of using topical anesthetics include their localized action with negligible systemic absorption, case of administration, painless application, and absence of edema at the surgical site that distorts wound margins in laceration repair.
Lidocaine-prilocaine cream (EMLA cream; AstraZeneca, Basiglio, Italy) is an eutectic mixture of 2.5% lidocaine and 2.5% prilocaine that is used widely as topical anesthetic for pediatric, dermatologic, reconstructive, and gynecologic minor procedures. Absorption from the genital mucosa is rapid, and onset time is between 5 and 10 minutes with an average duration of effective analgesia from 15-20 minutes; however, on intact skin, the cream should be applied for at least 1 hour to provide satisfactory dermal analgesia
Safety and efficacy of EMLA cream have been shown consistently in a number of clinical trials across many medical specialities since 1990 (Kaweski, 2008; Friedman et al., 2001).
EMLA cream provides analgesia by the release of lidocaine and prilocaine, which are two amide anesthetics, from the cream into the dem1al layers before penetrating the smooth and striated muscle and the individual axons within the nerve.
Other data
| Title | The Effect of Topical Application of Lidocaine – Prilocaine Cream on Pain Relief During Episiotom | Other Titles | تأثير الاستخدام الموضعي لليدوكايين بريلوكايين كريم في تخفيف الألم أثناء شق العجان | Authors | Afifi Ali Ali Al-Afifi | Issue Date | 2014 |
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