Evaluation of the Bidirectional Association Between Fe Profile and Direct Acting Antiviral Drugs Treatment Response For Chronic Hepatitis C Virus (HCV) Infection

Manal Abd Ellatif Mohamed


Abstract


HCV infection which affects nearly 3% of the human population, is a major cause of liver disease worldwide. The spectrum of this disease is quite variable, ranging from acute hepatitis to cirrhosis and hepatocellular carcinoma. It remains a major indication for liver transplantation in developed countries. Elevated iron parameters and mild iron overload are common in the liver of patients with chronic hepatitis C. Introduction of the novel highly effective and safe direct- acting antiviral has revolutionized the treatment of HCV-infected patients. Total cure is expected in more than 90% of chronically HCV-infected patients after 2 or 3 months of therapy. The study aims to conduct a comparison between the effect of Direct Acting Antiviral Drugs for chronic HCV infection on Iron profile & the impact of Iron profile in response to treatment. This study was conducted on ninety patients


Other data

Other Titles تقييم ثنائي الإتجاه للترابط بين الحديد والأستجابة لعلاج الإلتهاب الكبدي الوبائى (سى) المزمن بالأدوية الجديدة ذات العمل المباشرعلي فيروس (سى)
Issue Date 2018
URI http://research.asu.edu.eg/handle/12345678/47610


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