Acute Kidney Injury After Cardiac Surgery

Amr Mohamed Amer


Abstract


Acute kidney injury (AKI), a recognized complication of cardiac surgery with cardiopulmonary bypass (CPB) is associated with increased morbidity and mortality (15-30%) with approximately 1% of all the affected patients requiring dialysis. AKI-CS has a poor prognosis with the mortality ranging from 10-80% (uncomplicated AKI - 10% AKI with multi-organ failure >50%, AKI requiring renal replacement therapy - 80%). Risk Factors Are patient releated such as Age, Sex, Reduced LV function and procedure releated such as type of surgery and its duration. Patho-mechanisms Likely to involve the following mechanisms, processes, factors, and pathways: Toxins, Metabolic factors, Ischemia-reperfusion, Neurohormonal activation, Inflammation and Oxidative stress. And typically classified according to their timely occurrence into:-Pre-operative, intra-operative and post-operative events.


Other data

Other Titles الإصابه الكلويه الحاده ما بعد الجراحات القلبيه
Issue Date 2015
URI http://research.asu.edu.eg/handle/12345678/47717


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