Acute Kidney Injury After Cardiac Surgery
Amr Mohamed Amer;
Abstract
Acute kidney injury (AKI), a recognized complication of cardiac surgery with cardiopulmonary bypass (CPB) is associated with increased morbidity and mortality (15-30%) with approximately 1% of all the affected patients requiring dialysis.
AKI-CS has a poor prognosis with the mortality ranging from 10-80% (uncomplicated AKI - 10% AKI with multi-organ failure >50%, AKI requiring renal replacement therapy - 80%).
Risk Factors
Are patient releated such as Age, Sex, Reduced LV function and procedure releated such as type of surgery and its duration.
Patho-mechanisms
Likely to involve the following mechanisms, processes, factors, and pathways: Toxins, Metabolic factors, Ischemia-reperfusion, Neurohormonal activation, Inflammation and Oxidative stress. And typically classified according to their timely occurrence into:-Pre-operative, intra-operative and post-operative events.
AKI-CS has a poor prognosis with the mortality ranging from 10-80% (uncomplicated AKI - 10% AKI with multi-organ failure >50%, AKI requiring renal replacement therapy - 80%).
Risk Factors
Are patient releated such as Age, Sex, Reduced LV function and procedure releated such as type of surgery and its duration.
Patho-mechanisms
Likely to involve the following mechanisms, processes, factors, and pathways: Toxins, Metabolic factors, Ischemia-reperfusion, Neurohormonal activation, Inflammation and Oxidative stress. And typically classified according to their timely occurrence into:-Pre-operative, intra-operative and post-operative events.
Other data
Title | Acute Kidney Injury After Cardiac Surgery | Other Titles | الإصابه الكلويه الحاده ما بعد الجراحات القلبيه | Authors | Amr Mohamed Amer | Issue Date | 2015 |
Attached Files
File | Size | Format | |
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G10929.pdf | 987.19 kB | Adobe PDF | View/Open |
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