Preparation and characterization of antioxidant cosmeceutical formulations

Abstract

Abstract Preparation and characterization of antioxidant cosmeceutical formulations

Reactive oxygen species (ROS) are generated as by-products of cellular metabolism or upon exposure to external factors such as UV radiation. Excessive generation of ROS in the skin is believed to be involved in a variety of pathological conditions, including different types of cancers, immune suppression, photo-aging, photo carcinogenesis and even hair loss (alopecia). Recent research has demonstrated that using antioxidants as a therapeutic approach is very promising for treatment of dermatological diseases.

Melatonin is a neurohormone derived from serotonin and synthesized mainly in the pineal gland. Melatonin regulates the circadian rhythm, stimulates the immune system and acts as a cytoprotective agent. In addition, it has proved its capacity as a potent antioxidant.