THE ROLE OF CHRONIC INFECTIONS IN THE ETIOLOGY OF ATHEROSCLEROTIC CORONARY HEART DISEASES

Mogeda Mahdy Nasr Allah


Abstract


Atherosclerosis is the main underlying cause of coronary artery disease which is the most common cause of death in the world. The elassic risk factors such as Daibetus Mellutis, hyperension, smoking and hypercholesterolaemia can not explain the temporal and geographical variation in the accurrence of the disease. Intense research for other risk factors was done. Infectious agents and its relation to ischemic heart disease was studied. A number of infectious agents have been implicated in human atherosclerosis and include chlamydia pneumoniae, Helicobacter Pylori herpes virus particularly cytomegalovirus (CMV). The evidences of C. pneumoniae are stronger. There are lot oftherories showing possible mechanisms connecting C.Pneumoniae infection with the development ofiHD. One of them is the inflammatory mechanism. Another one is the immunological mechanism. Detecting a relation between infectious agents and IHD is of exterme importance as years later, the antichlamydial antibiotics may be involved in the regimen of treating cases of ischemic heart disease and ASO.


Other data

Other Titles دور العدوى المزمنة فى امراض تصلب الشرايين التاجية
Issue Date 2001
URI http://research.asu.edu.eg/handle/12345678/4824


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