Effect of Guar Gum On Lipid Metabolism, Plasma Glucose and Plasma Urea In Experimental Animals

Abstract

Sixty four male albino rats, Sprague Dawley strain, weighing (90-100g) were used. The rats were divided into eight groups of eight rats each. All rats were fed the different experimental diets, which had the same composition except for the fibre source, concentration and cholesterol content as the following: Group 1 : 5% cellulose (control). Group 2 : 5% cellulose + 1% cholesterol. Group 3 : 5% guar gum. Group 4 : 5% guar gum + 1% cholesterol. Group 5 : 10% guar gum. Group 6 : 10% guar gum + 1% cholesterol/ Group 7 : 15% guar gum. Group 8 : 15% guar gum + 1% cholesterol.

All rats were fed ad-libitum for 4 weeks, then subjected to the determination of: (1) Food intake, feed efficiency ratio. (2) Body weight gain. (3) Relative weights of organs (liver, kidney and spleen). (4) Plasma total cholesterol. (5) Hepatic cholesterol. (6) Plasma triacylglycerol (TAG). (7) Plasma high-density lipoprotein (HDL) cholesterol. (8) Plasma low-density lipoprotein (LDL) cholesterol. (9)Plasma very low-density lipoprotein (V-LDL) cholesterol.