A STUDY TO EVALUATE THE ROLE OF CALCIUM CARBONATE IN THE TREATMENT OF PREMENSTRUAL SYNDROME

Abstract

Premenstrual syndrome (PMS) is psyche>logical and somatic disorder or a group of disorders- characterized by somatic, affective, cognitive and behavioral disturbances tl1at appear during tl1e post-ovulatory phase of the menstrual cycle and tl1en resolve spontaneously rapidly at or near the onset of menses.

Premenstrual syndrome may be primary or secondary depending on the degree of underlying psychopathology:

In secondary PMS there is an underlying psychological disorder whose etiology is similar to that of common psychiatric disorders such as depression or anxiety. Both primary PMS and the cyclical component of secondary PMS are related to the ovarian cycle.

The range• of treatment approaches for PMS for which success has been claimed includes: • Nonpharmacological: Rest, isolation, psychotherapy, education, counseling, diet, hypnosis, acupuncture, bilateral oophorectomy, endometrial ablation, hysterectomy. " Nonhormonal: pyridoxine, essential fatty acids, vitamins, diuretics, aldosterone antagonists, clonidine, non-steroidal anti- inflammatories, beta-blockers, tranquilizers, anti-depressants. •• Hormonal: progesterone, oral contraception, testosterone, danazol, bromocriptine, GnRH analogues, Mifepristone.