125I BRACHYTHERAPY IN BRAIN TUMORS
Khaled Abdel Karim Mohamed;
Abstract
Malignant gliomas are heterogeneous group of tumors that are associated with• significant morbidity and mortality causing the majority of deaths due to primary brain malignancies.
Cytoreductive surgery followed by external bean radiotherapy has become the standard conventional treatment against which other treatments are compared, but even with •using such management, high-grade astrocytoma and glioblastoma multiforme are highly aggressive tumors with poor survival.
Brachytherapy (brachy, from the Greek for short distance) consists of placing sealed radioactive sources very close or in contact with the target tissue and for the last two decades, brachytherapy using 1251 was investigated in selected patients with malignant gliomas.
44 patients with primary or recurrent anaplastic astrocytoma or glioblastoma multiforme were treated using temporary implanted interstitial 1251 sources. All cases were treated at Ain Shams University Hospitals from December
1998 and November 2000.
Cytoreductive surgery followed by external bean radiotherapy has become the standard conventional treatment against which other treatments are compared, but even with •using such management, high-grade astrocytoma and glioblastoma multiforme are highly aggressive tumors with poor survival.
Brachytherapy (brachy, from the Greek for short distance) consists of placing sealed radioactive sources very close or in contact with the target tissue and for the last two decades, brachytherapy using 1251 was investigated in selected patients with malignant gliomas.
44 patients with primary or recurrent anaplastic astrocytoma or glioblastoma multiforme were treated using temporary implanted interstitial 1251 sources. All cases were treated at Ain Shams University Hospitals from December
1998 and November 2000.
Other data
| Title | 125I BRACHYTHERAPY IN BRAIN TUMORS | Other Titles | إستخدام اليود المشع 125 كمادة مشعة منزرعة بالأنسجة فى حالات أورام المخ | Authors | Khaled Abdel Karim Mohamed | Issue Date | 2001 |
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