ROLE OF THORACIC SURGERY IN MANAGEMENT OF INFECTION WITH MYCOBACTERIUM TUBERCULOSIS
Mohamed Samy El-Sayed Oraby;
Abstract
Background:
Tuberculosis is a multi-systemic disease with myriad presentations and manifestations. It is the most common cause of infectious disease-related mortality worldwide. TB remains one of the world’s deadliest communicable diseases. Mycobacterium TB, a tubercle bacillus, is the causative agent of TB.
Pulmonary tuberculosis is closely related to the history of thoracic surgery. A recent systematic review reported that pulmonary resection combined with anti¬-TB chemotherapy for multi-drug resistant tuberculosis has achieved treatment success rates in some settings of up to 88-92% of cases. Despite these favorable results, the role of surgery remains controversial in the most recently published guidelines.
Its indication is limited to the management of complicated forms of pulmonary TB and to cases in which medical treatment is failing210. Good cooperation between treating physicians and thoracic surgeons, as well as patients’ adherence to pre¬ and post-operative intervention chemotherapy can increase the success rate of MDR¬TB treatment.
Conclusion:
Surgery for tuberculosis should be limited to the management of complication or failure of medical treatment with proper patient selection and the timing of operations to avoid relapse and providing higher chance of cure, this needs cooperation between physicians and thoracic surgeons.
Key words:
Mycobacterium tuberculosis, Multi-drug resistant tuberculosis
Tuberculosis is a multi-systemic disease with myriad presentations and manifestations. It is the most common cause of infectious disease-related mortality worldwide. TB remains one of the world’s deadliest communicable diseases. Mycobacterium TB, a tubercle bacillus, is the causative agent of TB.
Pulmonary tuberculosis is closely related to the history of thoracic surgery. A recent systematic review reported that pulmonary resection combined with anti¬-TB chemotherapy for multi-drug resistant tuberculosis has achieved treatment success rates in some settings of up to 88-92% of cases. Despite these favorable results, the role of surgery remains controversial in the most recently published guidelines.
Its indication is limited to the management of complicated forms of pulmonary TB and to cases in which medical treatment is failing210. Good cooperation between treating physicians and thoracic surgeons, as well as patients’ adherence to pre¬ and post-operative intervention chemotherapy can increase the success rate of MDR¬TB treatment.
Conclusion:
Surgery for tuberculosis should be limited to the management of complication or failure of medical treatment with proper patient selection and the timing of operations to avoid relapse and providing higher chance of cure, this needs cooperation between physicians and thoracic surgeons.
Key words:
Mycobacterium tuberculosis, Multi-drug resistant tuberculosis
Other data
| Title | ROLE OF THORACIC SURGERY IN MANAGEMENT OF INFECTION WITH MYCOBACTERIUM TUBERCULOSIS | Other Titles | دور جراحة الصدر في التعامل مع حالات ميكروب الدرن الرئوي | Authors | Mohamed Samy El-Sayed Oraby | Issue Date | 2016 |
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