Retrospective Analysis of Clinicoepidemiological Factors in Gastric Cancer

Abstract

G astric cancer is one of the most common cancers worldwide (Jemal et al, 2011). In our study we reviewed of medical records on 102 patients including demographic data and clinic-pathological factors were reported, including age, sex, performance status (ECOG), comorbidities, personal habits, endoscopy and its finding, tumor characteristics, surgery, perioperative treatment, metastatic treatment, treatment response and survival rates were collected. Among the predisposing factors are: Helicobacter pylori infection, high salt intake, smoking, and in a small percentage of patients, a familial genetic component. More than 95% of stomach cancer cases are adenocarcinomas(Maria,2013). Our population under study had: median age of the studied population was 53 years (range: 29-76), male to female ratio as 1.2:1, majority of our patients (88.2%) had good ECOG performance status (≤ 2), (61.8%) of the patients were presented to us with stage IV disease, most common symptoms at presentation were abdominal pain in 58.8% and vomiting in 29.4% and the most common site of gastric cancer was pylorus in 37.3% then fundus in 15.7%. As regard treatment in patients with locoregional disease, only few patients received neoadjuvant line of treatment while most of non-metastatic patients received adjuvant treatment.