The Role of Diffusion Weighted MR Imaging in Assessment of Hepatic Malignancy after Radiofrequency Ablation

Abstract

Keywords: MRI-RFA-DWI-ADC DWI measures the ADC values, which relate to the movement of water molecules in vivo and indirectly reflect tissue micro-structural characteristics. The use of DWI in liver is relatively new, but very promising for the detection and differentiation of benign and malignant lesions before treatment and on follow-up after treatment. Besides, DWI is thought to be capable of evaluating the response to therapy of malignant tumors.In our study we concluded that DWI together with conventional imaging is a promising tool in the evaluation of the post RFA malignant liver tumors. Finally we could recommend a cut -off value 1.233×10−3mm2/sec, with t values below this level, express viability of the malignancy. After RF ablation, the ADC values increase above this limit. .