ROLE OF MRI WITH DIFFUSION WEIGHTED IMAGES IN EVALUATION OF RECTAL CARCINOMA
Mona Abdelaal Ali Mohamed;
Abstract
Rectal cancer is one of the most common tumors in industrialized countries and one of the most common malignant tumors of the gastrointestinal tract. Risk factors include polyposis syndromes, inflammatory bowel disease, and dietary imbalance between fat, protein and fiber.
The advances in preoperative therapies have led to the need of accurate preoperative staging to select those patients who are most likely to benefit from these interventions without subjecting others to unnecessary treatment.
MR imaging has become the most accurate technique in local staging of rectal cancer, this is due to advances in terms of imaging equipment, coils, and sequences that have progressively improved the technique, with a parallel increase in accuracy .The identification and staging of rectal cancers at MR imaging is largely based on differences in T2 signal intensity between the tumor, the mucosa and submucosal layers, the muscular layer, the perirectal fat, and the mesorectal fascia.
MRI can provide information regarding the site of tumor, the depth of mural and extramural tumor spread, involvement of the circumferential resection margin and indicate the extent of any sphincteric involvement.
Identification of nodal disease continues to be a problem for radiologists. The problem for morphologic imaging is their dependence on size criterion for diagnosis.
The aim of our study is to assess the role of magnetic resonance with diffusion in staging of rectal carcinoma in relation to histopathological findings.
In our study, we assessed the distance between the tumor and the MRF only on T2-weighted images, while we used DW imaging to detect viable tumor signal at the corresponding site, in case of primary rectal staging without neoadjuvant therapy we found that high-resolution MR imaging is a reliable and reproducible technique with high accuracy for predicting a negative CRM, the relationship of the tumor to the CRM, and the depth of tumor invasion outside the muscularis propria.
However, as regard the nodal staging ,although we rely on the morphology not only the size in assessment of nodal involvement, the assessment of nodal involvement remains a confounding factor with adding DWI there were increase in the
The advances in preoperative therapies have led to the need of accurate preoperative staging to select those patients who are most likely to benefit from these interventions without subjecting others to unnecessary treatment.
MR imaging has become the most accurate technique in local staging of rectal cancer, this is due to advances in terms of imaging equipment, coils, and sequences that have progressively improved the technique, with a parallel increase in accuracy .The identification and staging of rectal cancers at MR imaging is largely based on differences in T2 signal intensity between the tumor, the mucosa and submucosal layers, the muscular layer, the perirectal fat, and the mesorectal fascia.
MRI can provide information regarding the site of tumor, the depth of mural and extramural tumor spread, involvement of the circumferential resection margin and indicate the extent of any sphincteric involvement.
Identification of nodal disease continues to be a problem for radiologists. The problem for morphologic imaging is their dependence on size criterion for diagnosis.
The aim of our study is to assess the role of magnetic resonance with diffusion in staging of rectal carcinoma in relation to histopathological findings.
In our study, we assessed the distance between the tumor and the MRF only on T2-weighted images, while we used DW imaging to detect viable tumor signal at the corresponding site, in case of primary rectal staging without neoadjuvant therapy we found that high-resolution MR imaging is a reliable and reproducible technique with high accuracy for predicting a negative CRM, the relationship of the tumor to the CRM, and the depth of tumor invasion outside the muscularis propria.
However, as regard the nodal staging ,although we rely on the morphology not only the size in assessment of nodal involvement, the assessment of nodal involvement remains a confounding factor with adding DWI there were increase in the
Other data
| Title | ROLE OF MRI WITH DIFFUSION WEIGHTED IMAGES IN EVALUATION OF RECTAL CARCINOMA | Other Titles | دور الرنين المغناطيسى مع الرنين المغناطيسى الانتشارى فى تقييم سرطان المستقيم | Authors | Mona Abdelaal Ali Mohamed | Issue Date | 2014 |
Recommend this item
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.