Epstein - Barr Serum Specific Nuclear lgG in Malignant Lymphoproliferative Disorders
EMAN ABBAS MOHAMED;
Abstract
Epstein - Barr virus (EBV) is one the most common infectious agents of human found in all populations worldwide. It is the etiologic agents of infectious mononucleosis and is associated with Burkitt's lymphoma and nasopharyngeal carcinoma. It has been linked to a variety of other epithelial and lymphoid- derived proliferative diseases
The aim of this work was to estimate EBV serum specific nuclear IgG in patients with lymphoproliferative disorders to detect the association between EBV infection and these diseases comparing with the control group.
(1) This study was carried on 79 patients with malignant lymphoproliferative disorders. They were classified into 14 patients with Hodgkin lymphoma, 30 patients with non Hodgkin lymphoma and 35 patients with chronic lymphatic leukaemia. In addition, 15 apparently healthy individuals were included as a control group.
Blood samples were collected from all patients and
controls to determine EBV serum specific antibodies (IgG)
using ELISA technique.
(2) It was found that 7 out of 14 patients with Hodgkin's disease (50%), 21 out of 30 patients with chronic lymphatic leukaemia (29%) were positive for EBV lgG antibodies. While only 2 out of 15 controls (13%) were positive.
The aim of this work was to estimate EBV serum specific nuclear IgG in patients with lymphoproliferative disorders to detect the association between EBV infection and these diseases comparing with the control group.
(1) This study was carried on 79 patients with malignant lymphoproliferative disorders. They were classified into 14 patients with Hodgkin lymphoma, 30 patients with non Hodgkin lymphoma and 35 patients with chronic lymphatic leukaemia. In addition, 15 apparently healthy individuals were included as a control group.
Blood samples were collected from all patients and
controls to determine EBV serum specific antibodies (IgG)
using ELISA technique.
(2) It was found that 7 out of 14 patients with Hodgkin's disease (50%), 21 out of 30 patients with chronic lymphatic leukaemia (29%) were positive for EBV lgG antibodies. While only 2 out of 15 controls (13%) were positive.
Other data
| Title | Epstein - Barr Serum Specific Nuclear lgG in Malignant Lymphoproliferative Disorders | Other Titles | الأجسام المضادة ( ج ) لفيروس الابشتاين – بار فى السرطانات المختلفة للخلايا الليمفاوية | Authors | EMAN ABBAS MOHAMED | Issue Date | 1998 |
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