•, C l\ RBOfUR AN AND THE HE.RBI.ClD£ . . 2.4.-D ON M.tTOSIS AND MEIOSIS Of THE MOUSE
KAWSER MANSOUR EL-SHERBENY;
Abstract
1. The aim of the present investigations is to study the cytogenetic effect of the herbicide "2,4- D'' and the carbamate insecticide ''Carbofuran" on mouse bone-marrow cells and spermatocyte cells, in order to evaluate their potential mut agenecity.
2. The two pesticides were tested for:
• Induction of micronuclei in mouse bone-Marrow.
• Their ability to induce chromosome aberrations in mouse bone-marrow cells.
• Their ability to induce sister chromatid exchanges (SeE's) in mouse bone-Marrow cells.
• Their ability to induce chromosome aberrations in spermatocyte cells.
• The doses used in all test were:
a) "2, 4-D"
b) "Carbofuran"
30 mg/kg body wt.
0.025 mg/kg body wt.
3. Intraperitoneal and oral treatments with "2,4- D" and carbofuran induced a statistically
significant increase in the percentage of
2. The two pesticides were tested for:
• Induction of micronuclei in mouse bone-Marrow.
• Their ability to induce chromosome aberrations in mouse bone-marrow cells.
• Their ability to induce sister chromatid exchanges (SeE's) in mouse bone-Marrow cells.
• Their ability to induce chromosome aberrations in spermatocyte cells.
• The doses used in all test were:
a) "2, 4-D"
b) "Carbofuran"
30 mg/kg body wt.
0.025 mg/kg body wt.
3. Intraperitoneal and oral treatments with "2,4- D" and carbofuran induced a statistically
significant increase in the percentage of
Other data
| Title | •, C l\ RBOfUR AN AND THE HE.RBI.ClD£ . . 2.4.-D ON M.tTOSIS AND MEIOSIS Of THE MOUSE | Other Titles | التأثيرات الوراثية السمية للمبيد الحشرى الكربوفيران ومبيد الاعشاب 2,4D على الانقسام المتيوزى والميوزى فى الفأر | Authors | KAWSER MANSOUR EL-SHERBENY | Issue Date | 1996 |
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