•, C l\ RBOfUR AN AND THE HE.RBI.ClD£ . . 2.4.-D ON M.tTOSIS AND MEIOSIS Of THE MOUSE

KAWSER MANSOUR EL-SHERBENY,

Abstract


1. The aim of the present investigations is to study the cytogenetic effect of the herbicide "2,4- D'' and the carbamate insecticide ''Carbofuran" on mouse bone-marrow cells and spermatocyte cells, in order to evaluate their potential mut­ agenecity.

2. The two pesticides were tested for:

• Induction of micronuclei in mouse bone-Marrow.

• Their ability to induce chromosome aberrations in mouse bone-marrow cells.
• Their ability to induce sister chromatid exchanges (SeE's) in mouse bone-Marrow cells.
• Their ability to induce chromosome aberrations in spermatocyte cells.
• The doses used in all test were:


a) "2, 4-D"

b) "Carbofuran"

30 mg/kg body wt.

0.025 mg/kg body wt.



3. Intraperitoneal and oral treatments with "2,4- D" and carbofuran induced a statistically
significant increase in the percentage of


Other data

Title •, C l\ RBOfUR AN AND THE HE.RBI.ClD£ . . 2.4.-D ON M.tTOSIS AND MEIOSIS Of THE MOUSE
Other Titles التأثيرات الوراثية السمية للمبيد الحشرى الكربوفيران ومبيد الاعشاب 2,4D على الانقسام المتيوزى والميوزى فى الفأر
Authors KAWSER MANSOUR EL-SHERBENY
Issue Date 1996
URI http://research.asu.edu.eg/handle/12345678/50165

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