Synthesis of Some Fat Based Heterocycles from Olive Oil Production Waste Precursors

Abstract

This work has been carried out to investigate the utility of methyl octadecenoate for the synthesis of some new heterocyclic compounds pended to long chain fatty acid residue such as triazole, pyrazole, thiadiazole, thiadiazine, oxadiazole, 1,2,4- triazolo[3,4-b]-1,3,4-thiadiazole, triazalo[2,1-b]-1,3,4-thiadiazole, 1,2,4- triazolo[3,4-b]benzo[1,2-d]-1,3-oxazine, benzyo[1',2'-4,5]imidazo[1,2-c]triazole, 1,2,4-triazolo[1,5-a]pyrimidine, 1,2,4-triazolo[1 ,5-a]pyrimidine, imidazo[1,2- b][1,2,4]triazole, 1,3,4-triazolo[1 ,5-a]pyrimidine, [1,2,4]triazolo[5,1- c][1,2,4]triazine, 1,2,4-triazolo[1,5-c]pyrido[2',3'-e]-1,3,4-triazine, 1,2,4- triazolo[1 ,5-c]pyrimido[5',4'-e]-1,3,4-triazine, 1,2,4-triazolo[5,1-c]-pyrazino[4,3- e] 1,2,4-traizine, pyrazolo[5,1-c][1,2,4]triazine, and 1,2,4-triazolo[3,4- c][1,2,4]triazole derivatives of expected potential biological activity.