Isolation and Structure Elucidation of Bioactive Metabolites from Marine Organisms and Associated Endosymbionts
Mohamed Said Amin Elnaggar;
Abstract
Chemical investigation of three of the marine-derived fungal strains, Scopulariopsis sp.,
Alternaria sp. and Gliomastix sp. which were isolated from the Red Sea hard coral Stylophora
sp. yielded seventy-eight secondary metabolites. In which, Scopulariopsis sp. yielded twentynine
metabolites
among
which
six
are
new
natural
products
including,
two
new
xanthones,
12dimethoxypinselin
(1) and 12-O-acetyl-AGI-B4 (2), two new bisabolane-type sesquiterpenes,
11,12-dihydroxysydonic acid (15) and 1-hydroxyboivinianic acid (16), alongside with one new
alkaloid, scopulamide (21) and one new α-pyrone derivative, scopupyrone (26) alongside with
twenty-three known compounds (3 – 11, 12 – 14, 17 – 20, 22 – 25, 27 – 29) including xanthone,
sesquiterpene, biphenyl ether and alkaloid derivatives.
Alternaria sp. and Gliomastix sp. which were isolated from the Red Sea hard coral Stylophora
sp. yielded seventy-eight secondary metabolites. In which, Scopulariopsis sp. yielded twentynine
metabolites
among
which
six
are
new
natural
products
including,
two
new
xanthones,
12dimethoxypinselin
(1) and 12-O-acetyl-AGI-B4 (2), two new bisabolane-type sesquiterpenes,
11,12-dihydroxysydonic acid (15) and 1-hydroxyboivinianic acid (16), alongside with one new
alkaloid, scopulamide (21) and one new α-pyrone derivative, scopupyrone (26) alongside with
twenty-three known compounds (3 – 11, 12 – 14, 17 – 20, 22 – 25, 27 – 29) including xanthone,
sesquiterpene, biphenyl ether and alkaloid derivatives.
Other data
| Title | Isolation and Structure Elucidation of Bioactive Metabolites from Marine Organisms and Associated Endosymbionts | Authors | Mohamed Said Amin Elnaggar | Issue Date | 2017 |
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