Assessment of the Effect of Long Term Inhalation of Corticosteroids (ICS) for Asthma control in children on fat distribution and bone density.

Abstract

sthma is the most common chronic disease of childhood. It is a worldwide problem that affect approximately 300 million people worldwide. Inhaled corticosteroids (ICS) are recommended as first line anti-inflammatory therapy for treatment of asthma in children for more than 20 years. During this time a substantial number of studies have been performed for evaluation of safety and efficacy of this therapy. The present work is a case control study conducted to assess the effect of long term inhalation with corticosteroids (ICS) for asthma control in children on fat distribution and bone density. We studied 120 children of both sexes ,with ages ranging from 5 to 10 years. They were classified into 3 groups . group I, included 40 children of both sexes (20 males and 20 females) with moderate asthma and given ICS in moderate