ROLE OF MAGNETIC RESONANCE IMAGING IN EVALUATION OF PROSTATIC DISORDERS

Abstract

Adenocarcinoma of the prostate is an extremely common malignancy in men and second leading cause of death from cancer in men. Traditionally, screening for prostate carcinoma has included a digital rectal examination (ORE). More recently, however, measurement of serum prostate-specific antigen level (PSA), endorectal ultrasound and ultrasound-guided biopsy in patients with elevated PSA level > 4 ng/ml has been added to the screening protocol. The high prevalence of prostate carcinoma underscore the imp0rtance of developing an accurate, reproducible and generally avail::mle method fc,• staging.

Benign prostatic hyperplasia (BPH) occur in most men over the age of 60 years with genitourinary disease and often causes substantial bladder outt1ow obstruction.

Numerous cystic lesions occur in the prostate and occasionally cause ejaculatory dysfunction. Acute prostatitis is most commonly caused by direct extension from the posterior urethra or urinary bladder, chronic prostatitis is much more common than acute form, is frequently recurrent, and often clinically silent. A prostatic abscess usually develop as a sequel of prostatitis and differentiation between both entities may be difficult on clinical background.

• The aim of this work was to study the role of MRI in evaluation of variable prostatic disorders and to compare the results of MRI with those of ORE, PSA, TRUS, operative and histopathological results.

This work was conducted on 250 consecutive patients examined with the following procedures:

1. Serum prostate specific antigen (PSA). 2. Digital rectal examination (DER): Performed by experienced urologists. 3. MRI 4. TRUS 5. TRUS guided biopsy: for 122 cases. 6. Bone scan: was done for 53 cases with biopsy proven cancer.