EFFECT OF SOME PLANT EXTRACTS ON RENAL FUNCTIONS IN EXPERIMENTAL ANIMALS

Abstract

Renal failure describes a medical condition in which the kidneys fail to adequately filter toxins and waste products from the blood. It can be divided into two categories: chronic renal failure (CRF) which is often not reversible and acute renal failure (ARF). A number of other diseases or health problems may cause either form of renal failure. ARF which is recently called acute kidney injury (AKI) is a critical clinical problem with a high mortality rate. Management includes supportive care, such as renal replacement therapy (hemodialysis), as well as treatment of the underlying disorder. In recent years, great efforts have been focused on natural compounds and herbal constituents without toxic effects to provide novel therapeutic agents for ARF. Therefore, this study was aimed to evaluate the curative effects of gum Arabic and Boswellia sp. administered in drinking water (10% w/v) for rats affected with ARF induced by glycerol or paracetamol. In order to achieve these objectives, the followin