CYTOKINES IN ALOPECIA AREATA
Reham Ezz-EI Dawla EI-Sharkawy;
Abstract
Alopecia areata is a common, non scarring reversible disorder of hair loss (Tobin et a/;, (1997). Although, the pathogenesis of AA is still unknown evidence is accumulating that AA is an immunologically mediated disease. (Baadsgaad,
1991)
Immunomodulatory cytokines not only act as mediators of immunity and inflammation but also regulate cell proliferation and differentiation, and may play an important role in regulating hair growth. (Philpott et al., 1996)
The present study was carried out on 40 patients with AA attending Dermatology Outpatient Clinic of Sohag University Hospital. 34 patients had localized AA and 6 patients had alopecia totalis. 10 healthy individuals were selected as control.
The results were as follows:
(1) Clinical findings:
- In the studied group of patients: The age ranged from 6 to 50 years with a mean 23.93 ± 12.42 years. The age of the control ranged from 18 to 26 years with a mean 21.50 ±
3.50.
- Of the patients males were 25 (62.5%) and females were 15 (37.5%), in the control group males were 4 (40%) and females were 6 (60%).
The duration of the disease in the studied patients ranged from 2 days to 4 years with a mean (155.40 ± 303.35).
1991)
Immunomodulatory cytokines not only act as mediators of immunity and inflammation but also regulate cell proliferation and differentiation, and may play an important role in regulating hair growth. (Philpott et al., 1996)
The present study was carried out on 40 patients with AA attending Dermatology Outpatient Clinic of Sohag University Hospital. 34 patients had localized AA and 6 patients had alopecia totalis. 10 healthy individuals were selected as control.
The results were as follows:
(1) Clinical findings:
- In the studied group of patients: The age ranged from 6 to 50 years with a mean 23.93 ± 12.42 years. The age of the control ranged from 18 to 26 years with a mean 21.50 ±
3.50.
- Of the patients males were 25 (62.5%) and females were 15 (37.5%), in the control group males were 4 (40%) and females were 6 (60%).
The duration of the disease in the studied patients ranged from 2 days to 4 years with a mean (155.40 ± 303.35).
Other data
| Title | CYTOKINES IN ALOPECIA AREATA | Other Titles | السيتوكاينز فى مرض الثعلبة | Authors | Reham Ezz-EI Dawla EI-Sharkawy | Issue Date | 1999 |
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