EFFECT OF ANGIOTENSIN CONVERTING ENZYME INHIBITORS VERSUS LONG ACTING CALCIUM ANTAGONISTS IN TREATMENT OF CHRONIC AORTIC REGURGITATION
ALI AHMED YOUSSEF;
Abstract
+ The basic cause of chronic AR in our society is RHD.
• Chronic AR is more prevalent in males. The area of gender difference in patients with chronic AR needs to be more stressed, also, is waiting for explanation. A larger
"
population based survey may help this point, especially in
. . \ .
our society, and provide the important lacking figures of
')r'• •••
'the prevalence and true magnitude of the problem of
,•,
rheumatic valvular heart disease.
• Until now, nifedipine has been recognized as the most effective among vasodilators in AR patients. On the basis of their. vasodilator mode of action, ACE inhibitors-which have been shown to be highly effective in terms of their management of hypertension and heart failure- could be expected to produce equally positive effects in the
• treatment of AR patients as were seen with nifedipine.
• In studies of long-term vasodilator therapy in patients with chronic AR, a reduction of left ventricular volumes and regurgitant fraction, with or without an increase in ejection fraction, has been observed during treatment with hydralazine, nifedipine and ACE inhibitors.
• Chronic AR is more prevalent in males. The area of gender difference in patients with chronic AR needs to be more stressed, also, is waiting for explanation. A larger
"
population based survey may help this point, especially in
. . \ .
our society, and provide the important lacking figures of
')r'• •••
'the prevalence and true magnitude of the problem of
,•,
rheumatic valvular heart disease.
• Until now, nifedipine has been recognized as the most effective among vasodilators in AR patients. On the basis of their. vasodilator mode of action, ACE inhibitors-which have been shown to be highly effective in terms of their management of hypertension and heart failure- could be expected to produce equally positive effects in the
• treatment of AR patients as were seen with nifedipine.
• In studies of long-term vasodilator therapy in patients with chronic AR, a reduction of left ventricular volumes and regurgitant fraction, with or without an increase in ejection fraction, has been observed during treatment with hydralazine, nifedipine and ACE inhibitors.
Other data
| Title | EFFECT OF ANGIOTENSIN CONVERTING ENZYME INHIBITORS VERSUS LONG ACTING CALCIUM ANTAGONISTS IN TREATMENT OF CHRONIC AORTIC REGURGITATION | Other Titles | تأثير مثبطات الانزيم المحول للأنجيوتنسين مقارنة بمضادات الكالسيوم ممتدة المفعول فى علاج ارتجاع الاورطى المزمن | Authors | ALI AHMED YOUSSEF | Issue Date | 2000 |
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