Comparative Study of Induction of Labour at term by Misoprostol Vaginal Insert versus Dinoprostone Vaginal Insert

Abstract

I nduction of labor should be used in the most efficient way possible that will result in a favourable obstetric outcome with minimum fetal morbidity This study was conducted at Obstetrics &gynecology department,Ain shams University, maternity hospital in the period of timebetween June 2013 to February 2014. The aim of this study is to compare the efficacy, safetyofadose of 25µgvaginal misoprostol versus 3mg dinoprostone vaginal insertininduction of labor at term. The total number of patients studied was 200 patients, divided into two groups;the first group (A) included 100 patients who received vaginal misoprostol 25 µg every 4hours for a maximum of 3 doses, the second group (B) included 100 patients who received dinoprostone 3mg vaginally every 6hours for a maximum of 2 doses. The current study found that dinoprostonehas a better chance for NVDand a lesser probability to CSand a shorter induction delivery interval in comparing to misoprostol. While both drugs were equal regardingmaternal and fetal safety. The present study showedthat it is safe and worthy to induce labor by the two drugs without forgetting the precautionsand the close supervision to the mother and the fetus.